Absidia corymbifera

 




Lungs (DPI-5).
Pneumonic consolidation of antero-ventral lobes.





Lung (DPI-1).
Hyphaes and spores of Absidia corymbifera along with purulent exudate in the lumen of a small bronchiole. GMS-H&E, 300 X.



Lung (DPI-1).
Fungal hyphae extending from the lumen of the bronchiole into mthe adjoining parenchyma.
GM¿S-H&E, 300 X.


Lung (DPI-1).
Fungal hyphae surrounded by early pyogranuloma.
GMS-H&E, 300 X.





Lung (DPI-1).
Mycotic thrombosis (T), vasculitis (V) and purulent bronchiolitis (B) along with fungal hyphae in the lumen of a bronchiole.
GMS-H&E, 150 X.


Lung (DPI-3).
Large pyogranuloma in the parenchyma with increased number of long hyphae.
GMS-H&E, 150 X.



Lung (DPI-3).
Giant cell granulomas, showing phagocytized digested fungal particles in the giant cells (arrow). GMS-H&E, 300 X.

Lung (DPI-15).
Large chronic pyogranuloma.
GMS-H&E, 75 X.


Lung (DPI-15). Large chronic pyogranuloma showing cross sections of distorted fungal hyphae (arrow) phagocytized by giant cells. GMS-H&E, 150 X.


Lung (DPI-20). Chronic pyogranuloma encircled by severe infiltration of lymphocytes and fibrous tissue capsule. GMS-H&E, 75 X.


Brain (DPI-5). Cerebrum revealing glia nodule formation in the neuropil.
GMS-H&E, 150 X.


Brain (DPI-5). Severe perivascular lymphocytic cuffin in the cerebrum.
GMS-H&E, 150 X.


Kidney (DPI-5). Vacuolar degeneration in the tubular epithelium of the kidney.
GMS-H&E, 150 X.



Photographs obtained from: G Singh, PP Gupta, N Sood, H Singh Banga, S Kumar Jand. Sequential pathological studies in Asian water buffaloes infected intracheally with Absidia corymbifera.
Rev Iberoam Micol 1998; 15: 146-150.






Esporangios de Absidia corymbifera
(azul-algodón de lactofenol X100, 3º día de crecimiento).



Photograps obtained from: A del Palacio, MJ Ramos, A Pérez, A Arribi, I Amondarain, S Alonso, MC Ortíz. Five cases of zygomycosis.
Rev Iberoam Micol 1999; 16: 50-56.









Cut surfaces of the lung of group C animal (DPI-10), showing most extensive greyish mycotic lesions.





Cut surfaces of the lung of group M animal (DPI-10) showing less severe and less extensive greyish mycotic lessions than seen in group C animal.



Cut surfaces of the lung of group A animal (DPI-10) showing least extensive mycotic lessions.







Lung (DPI-1). Clumps of sporangiospores of Absidia corymbifera (arrow), surrounded by neutrophilic infiltration.
GMS-H&E 300 X.





Lung (DPI-3). Pyogranuloma with fungal elements in the centre (arrow), surrounded by eosinophilic Splendor-Hoeppli bodies. GMS-H&E 300 X.




Lung (DPI-3). Pyogranuloma with fungal elements in the centre (arrow), surrounded by eosinophilic Splendor-Hoeppli bodies.
PAS stain 300 X.




Lung (DPI-5). Phagocytosed fungal element (arrow) in foreign body giant cell.
GMS-H&E 1000 X.




Lung (DPI-5). Phagocytosed fungal element (arrow) in foreign body giant cell.
PAS stain 300 X.




Lung of group M animal (DPI-5). Severe neutrophilic reaction arround the fungal element (arrow). GMS-H&E 1000 X

.




Lung of group C rabbit (DPI-10). Foci of caseative necrosis. GMS-H&E 70 X.





Lung of group A animal (DPI-15). Disintegrated fungal granules in the macrophages.
GMS-H&E 1000 X.



Photographs obtained from: J Sondhi, PP Gupta, N Sood. Effect of immunosuppression on the pathogenesis of respiratory zygomycosis in rabbits intranasally infected with Absidia corymbifera.
Rev Iberoam Micol 1999; 16: 107-110.